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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: MiR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition and Upregulates Expression of Tight Junction Protein Claudin-5 in Human Upper Tract Urothelial Carcinoma Cells
doi: 10.3390/ijms18081826
Figure Lengend Snippet: Expression profiles of miRNAs in human UTUC tumor and non-tumor samples. Three tumor (T1–T3; light blue to navy blue) and three adjacent normal tissues (N1–N3; orange-yellow-green) were subjected to RNA extraction and NGS-miRNA sequencing through the Illumina MiSeq platform. ( A ) Heat-map clustering analysis was conducted to examine the overall miRNA expression profiles among samples. A line scatterplot was used to present miRNA expression profiles; ( B ) Downregulation of miR-30a-5p in UTUC tumor tissues ( n = 22) compared with adjacent normal controls ( n = 14) by RT-qPCR analysis. The asterisk denotes p < 0.001 using an unpaired t -test.
Article Snippet: The small RNA library construction and
Techniques: Expressing, RNA Extraction, Sequencing, Quantitative RT-PCR